Genetic Breast Cancer Risk Assessment

Easy to use at-home DNA saliva test to determine your personal risk of developing breast cancer for women aged 30+

MyBreastRisk combines genetic, family history and lifestyle factors to determine your personal lifetime breast cancer risk.

  • No need for a GP visit
  • At-home DNA saliva sample collection kit
  • Online family history and lifestyle questionnaire
  • Includes personalised screening programme
  • Allows you to manage your breast cancer risk

 

Why should I order MyBreastRisk?

MyBreastRisk was the first commercially available test to combine genetic, family history and lifestyle factors to determine a women's personal lifetime breast cancer risk. Discover your personal breast cancer risk with DNA science in combination with lifestyle and family history.

Why should I order MyBreastRisk?

Professor Gordon Wishart, Chief Medical Officer

Discover your personal breast cancer risk with our innovative at-home saliva DNA test, combined with an internationally-validated family history and lifestyle questionnaire.

Frequently Asked Questions

Why should I use MyBreastRisk?

MyBreastRisk was the first commercially available test to combine genetic, family history and lifestyle factors to determine your personal lifetime breast cancer risk.

In humans, 99.9% of the building blocks that make up our DNA are the same, but a SNP (single nucleotide polymorphism, pronounced SNIP) is a single building block that is altered and kept through heredity. It is these SNPs that give us our unique appearance and make us different from each other, but they can also be linked to an increased risk of certain diseases such as breast cancer. Unlike the well-publicised breast cancer genes BRCA1 and BRCA 2, which are incredibly rare in the population but confer a massive lifetime breast cancer risk of up to 60-90% if present, SNPs are much more common in the population and each SNP confers a small increased breast cancer risk. We now know of at least 77 SNPs that increase breast cancer risk and the more you have, the higher the risk.

Analysis of all 77 SNPs can now be performed on a saliva DNA sample, the result of which when combined with a lifestyle and family history questionnaire provides a risk score, that can stratify women into different levels of breast cancer risk (low, moderate or high risk). The risk score allows women at higher lifetime risk of breast cancer to start breast screening at an earlier age, and have more frequent screening, whilst women at lower risk require less screening. There is good scientific evidence to show that this risk-stratified type of breast screening is more effective.

How do I order MyBreastRisk?
  • You can order your MyBreastRisk at-home sample collection test kit here . The test kit will be delivered to your home in discrete packaging.
  • The cost of the MyBreastRisk test at-home kit is £295.00.
  • MyBreastRisk is suitable for women aged 30+ years.
What does MyBreastRisk include?
  • An online breast cancer risk-assessment questionnaire based on the validated Tyrer-Cuzick model.*
  • Saliva DNA sample collection kit. You can view the kit instructions here.

*The Tyrer-Cuzick model, or IBIS tool, is used to estimate the likelihood of a woman developing breast cancer over the course of her lifetime.

For women who do not know their medical family history, our simple saliva DNA test provides an excellent alternative way to discover your breast cancer risk.

What do I do with MyBreastRisk kit when I have completed it?
  • Complete the at-home test by following the simple instructions provided in the test kit.
  • Return your sample to our laboratory by Freepost.
  • Our team of specialists will analyse your test results.
When do I get my test results back?
  • You will receive your results and personalised breast screening programme by password protected email within eight weeks of our laboratory receiving your test sample.
What can I expect from my test results?
  • Results will be available within eight weeks of when your sample is sent off to our laboratory.
  • Results from the SNP DNA test and the questionnaire are combined to give an accurate Lifetime Risk Score.
  • Lifetime Risk Score:  You will be advised which of the three risk categories you fall into for developing breast cancer: 'Average', 'Moderate' or 'High Risk'.
  • Each category will be given very clear guidelines on future screening recommendations.
  • Anyone considered to be within the 'High Risk' group will be offered a free genetic counselling session to discuss specific risk reduction strategies or further genetic testing.
Disclaimer

Although MyBreastRisk will not prevent breast cancer, it can help you to determine your risk and ensure you are having the most appropriate screening. Those women in the 'Moderate' or 'High Risk' groups can access NHS services to discuss strategies to reduce their risk. 

You will be empowered to take control of your own breast cancer risk and will be able to make lifestyle choices and behaviour changes that will help you in the future.