Prostate Cancer Genetic Counselling and Testing

Trusted genetic testing for prostate cancer risk

Take control of your prostate health with Check4Cancer

Check4Cancer’s Prostate Cancer Gene Testing is a specialised genetic test designed for individuals with prostate cancer or a strong family history of the disease.

This advanced test examines the DNA of key genes known to be associated with an increased risk of developing prostate cancer. Performed on a simple saliva sample, it offers a fast, accurate, and non-invasive way to assess your genetic risk.

Before you undertake any genetic testing, it is important that you speak with a counsellor. Find out more about our counselling service.

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* Includes a one-hour phone consultation with a genetic counsellor.
£945

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The benefits of genetic testing for prostate cancer

Genetic testing empowers you to take control of your health with guidance from knowledgeable professionals. Here’s how it helps:

Confidence through knowledge:

Gain peace of mind by understanding your risk and taking proactive steps toward prevention or early detection.

Personalised care:

Use your test results to shape treatment plans that align with your unique health needs.

Expert guidance:

Our compassionate counsellors explain every detail of the process and results, providing clarity and reassurance.

Timely action:

Knowing your risk can enable earlier interventions for better outcomes.

Why choose Check4Cancer for your prostate cancer gene testing?

Understanding your genetic risk can empower you to take proactive steps to protect your health. Our service provides not just a test, but a complete support system, including expert guidance and personalised resources, to ensure you feel confident every step of the way. 

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Fast and accurate results

Our genetic testing process is reliable and quick, and ensures the highest standards of accuracy. 

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Guidance from expert genetic counsellors

 A national network of registered genetic counsellors is here to guide you before and after your genetic test. They’ll explain the testing process, provide support, and help you make informed decisions. 

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Personalised insights for future planning 

Your test results may influence your treatment options, choice of chemotherapy, and approaches to prevent future cancer. 

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Comprehensive support 

We offer a 1-hour phone or virtual consultation with an expert counsellor to answer your questions and address your concerns.

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What’s Included?

  • A detailed analysis of genes linked to prostate cancer risk.
  • Pre- and post-test genetic counselling to support you throughout your testing journey.
  • Actionable recommendations tailored to your results.
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Why genetic testing matters

Early detection saves lives

Knowing your genetic predisposition enables you to take preventive measures, increasing the odds of early detection if cancer develops.

Individualised care for your needs

With genetic insights, you can collaborate with your healthcare team to create a personalised medical plan.

Why Check4Cancer’s Prostate Cancer Gene Testing is different?

Our service goes beyond genetic testing. We understand the emotional and physical challenges of navigating cancer risk, which is why we offer the expertise, empathy, and support you need. 

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Why Check4Cancer’s Prostate Cancer Gene Testing is Different

Our service goes beyond genetic testing. We understand the emotional and physical challenges of navigating cancer risk, which is why we offer the expertise, empathy, and support you need.

When you choose ProstateGene, you’re backed by a first-class clinical team and a supportive community committed to delivering trusted and compassionate care.

Take the first step towards understanding your health. Prostate gene testing offers a safe, accurate, and supportive way to assess your risk for prostate cancer.

Schedule your consultation and genetic test today – because it’s always better to know.

Look after your health with clarity, confidence, and control. We are here to support you every step of the way.

FAQs

Is prostate cancer hereditary?

Most cases of prostate cancer occur by chance, but about 10% have a familial link. In some families, a genetic variant may be responsible. Identifying this can help guide cancer screening and risk-reducing strategies for family members.

What are the signs that prostate cancer might be hereditary in my family?

You may have an increased genetic risk if you or close relatives have:

  • Prostate cancer diagnosed before age 55
  • A family history of prostate, breast, ovarian, or pancreatic cancer
  • Multiple close relatives with prostate cancer across generations
  • An inherited gene variant in a prostate cancer risk gene, such as BRCA1 or BRCA2
What genes are linked to hereditary prostate cancer?

Several genes are associated with an increased risk of prostate cancer. At Check4Cancer, patients having cancer treatment who have insurance are usually tested for these 9 genes. They include:

  • ATM, BRCA1, BRCA2, CHEK2, EPCAM, HOXB13, MLH1, MSH2, MSH6   

A more comprehensive panel is also available to self-pay patients, including additional genes such as.

APC, ATM, BAP1, BARD1, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CDK4, CDKN2A, CHEK2, EPCAM, HOXB13, MLH1, MSH2, MSH6, MUTYH, NF1, NTHL1, PALB2, PMS2, POLD1, POLE, PTEN, RAD51C, RAD51D, SMAD4, STK11, TP53, VHL

How can genetic testing help with prostate cancer risk?

Genetic testing can:

  • Identify if you have a higher risk of developing prostate cancer
  • Help tailor cancer screening and prevention strategies
  • Guide treatment decisions, such as targeted therapies
What are the possible results of a prostate genetic test?
  • Pathogenic variant found – A gene variant  that increases prostate cancer risk is detected. Extra screening and/or risk-reducing measures will be recommended.
  • Variant of uncertain significance (VUS) – A genetic change is found, but it’s unclear if it increases cancer risk. Screening recommendations will be based on family history.
  • No variant found – No known risk-increasing variant is detected, but this does not rule out a genetic predisposition. Cancer screening may still be beneficial.
What happens if I test positive for a pathogenic variant?

If a pathogenic variant is found, your specific cancer risks depend on the gene involved. You may be offered:

  • More frequent PSA tests and MRI scans to detect prostate cancer early
  • Screening for other cancers if associated with your genetic risk
  • Risk-reducing options, such as medication or, in some cases, surgery
  • Genetic testing for close relatives to determine if they also carry the mutation
What screening is recommended for people at increased risk of prostate cancer?
  • Regular PSA blood tests and MRI scans are recommended for men at higher genetic risk.
  • Screening recommendations depend on specific genetic variants and family history.
Can lifestyle changes help lower prostate cancer risk?

Yes, maintaining a healthy lifestyle may help reduce prostate cancer risk. Recommendations include:

  • Eating a balanced diet rich in vegetables and low in processed meats
  • Maintaining a healthy weight
  • Engaging in regular physical activity
  • Avoiding smoking and limiting alcohol intake
Should I consider risk-reducing surgery?

Surgery is rarely recommended for prostate cancer risk reduction, but in certain high-risk cases, doctors may discuss preventive options tailored to your genetic profile.

What are the warning signs of prostate cancer?

It’s important to be aware of symptoms and seek medical advice if you notice:

  • Frequent or difficult urination
  • Blood in the urine or semen
  • Pain in the lower back, pelvis, or hips
  • Erectile dysfunction

Most people with these symptoms do not have cancer, but it's always best to check with a doctor.

Who is at higher risk of prostate cancer?

The risk of prostate cancer increases with age, which is why screening is recommended from age 50. However, additional risk factors include:

  • A family history of prostate, breast, or ovarian cancer
  • African or Caribbean ancestry (higher genetic predisposition)
  • Certain inherited genetic variants

If you have any of these risk factors, talk to your doctor about whether earlier screening is appropriate.

Check4Cancer’s Prostate Screening Test provides screening for men without symptoms aged 40+

Take charge of your prostate health today

Understanding your genetic risk is a powerful tool. Check4Cancer’s Prostate Cancer Gene Testing provides the knowledge, expert support and guidance you need to make informed health decisions.

Call us on: 03330 919 650
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Professor Andrew Beggs

Clinical Advisor for Bowel Cancer & Genetics

Professor Andrew Beggs is a Professor of Cancer Genetics & Surgery at the University of Birmingham and University Hospitals Birmingham NHS Foundation Trust. He runs a diverse research group of scientists and clinicians studying the molecular determinants of response to cancer treatments using organoid models and next-generation sequencing models. He is also an active cancer clinician, running a familial cancer clinic for the West Midlands Region and one of the national gastrointestinal polyposis centres. Professor Beggs acts as a scientific adviser to the UK Department of Health and Social Care and Genomics England.

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