Prostate Cancer Genetic Counselling and Testing

Trusted genetic testing for prostate cancer risk

Take control of your prostate health with Check4Cancer

Check4Cancer’s Prostate Cancer Gene Testing is a specialised genetic test designed for individuals with prostate cancer or a strong family history of the disease.

This advanced test examines the DNA of key genes known to be associated with an increased risk of developing prostate cancer. Performed on a simple saliva sample, it offers a fast, accurate, and non-invasive way to assess your genetic risk.

Before you undertake any genetic testing, it is important that you speak with a counsellor. Find out more about our counselling service.

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* Includes a one-hour phone consultation with a genetic counsellor.
£945

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The benefits of genetic testing for prostate cancer

Genetic testing can play an important role in
helping you take a proactive approach to prostate health. When combined with
expert counselling, it provides clarity, reassurance, and personalised
guidance.

Benefits include:

  • Confidence through knowledge

Understanding whether inherited genetic factors may influence your prostate cancer risk can provide peace of mind and reduce uncertainty.

  • Personalised screening and monitoring

Results can help inform when screening should begin and how closely prostate health should be monitored.

  • Expert guidance and support

Specialist genetic counsellors explain the process and results clearly, ensuring you are supported at every stage.

  • Early, informed action

Identifying increased risk may allow for earlier or more tailored surveillance, when outcomes are often more favourable.

Why choose Check4Cancer for your prostate cancer gene testing?

Understanding your genetic risk can empower you to take informed steps to protect your health. At Check4Cancer, we offer more than a genetic test — we provide a fully supported service designed around you. Our prostate cancer genetic testing includes:

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Fast and accurate results

Testing is conducted to high clinical standards, using reliable, validated methods.

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Guidance from expert genetic counsellors

Our national network of registered genetic counsellors supports you before and after testing, helping you make informed decisions.

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Personalised insights for future planning 

Results may help guide screening, monitoring, and conversations with your healthcare team.

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Comprehensive support 

Every test includes a one-hour phone or virtual consultation with a genetic counsellor to discuss your results and next steps.

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What’s Included?

  • Analysis of genes linked to prostate cancer risk
  • Pre- and post-test genetic counselling
  • Clear, personalised recommendations based on your results
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Why genetic testing matters

Early detection and informed prevention

Some prostate cancers are linked to inherited
genetic changes. Identifying these early can help guide proactive screening and monitoring, increasing the chances of detecting cancer at an earlier, more treatable stage.

Personalised care based on your risk

Genetic insights allow you and your healthcare team to tailor screening and surveillance to your individual risk profile, rather than relying on a one-size-fits-all approach.

Clarity for you and your family

Understanding inherited risk can also provide valuable information for family members, helping them make informed decisions about their own health and screening.

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Why Check4Cancer’s Prostate Cancer Gene Testing is Different

At Check4Cancer, genetic testing is never offered in isolation.

We recognise that understanding genetic risk can feel complex and, at times, overwhelming. That’s why our service combines accurate testing with expert counselling, clinical oversight, and
compassionate support.

When you choose Check4Cancer, you benefit from:

  • A counselling-led approach that prioritises understanding, not just results
  • Clear explanations tailored to your situation
  • Support in interpreting results and deciding on next steps

Our focus is on helping you make confident,
informed decisions about your prostate health.

FAQs

Is prostate cancer hereditary?

Most cases of prostate cancer occur by chance, but around 10% are linked to inherited genetic factors. Genetic testing can help identify whether hereditary risk may be relevant for you and guide screening decisions.

What are the signs that prostate cancer might be hereditary in my family?

You may have an increased genetic risk if you or close relatives have:

  • Prostate cancer diagnosed before age 55
  • A family history of prostate, breast, ovarian, or pancreatic cancer
  • Multiple close relatives with prostate cancer across generations
  • An inherited gene variant in a prostate cancer risk gene, such as BRCA1 or BRCA2
What genes are linked to hereditary prostate cancer?

Several genes are known to be associated with prostate cancer risk, including BRCA1 and BRCA2. A genetic counsellor can explain which genes are tested and why they are relevant.

How can genetic testing help with prostate cancer risk?

Genetic testing can:

  • Identify if you have a higher risk of developing prostate cancer
  • Help tailor cancer screening and prevention strategies
  • Guide treatment decisions, such as targeted therapies
What are the possible results of a prostate genetic test?
  • Pathogenic variant found – A gene variant  that increases prostate cancer risk is detected. Extra screening and/or risk-reducing measures will be recommended.
  • Variant of uncertain significance (VUS) – A genetic change is found, but it’s unclear if it increases cancer risk. Screening recommendations will be based on family history.
  • No variant found – No known risk-increasing variant is detected, but this does not rule out a genetic predisposition. Cancer screening may still be beneficial.
What happens if I test positive for a pathogenic variant?

A positive result does not mean you will definitely develop cancer. Your genetic counsellor will explain what the result means and discuss appropriate next steps, which may include tailored screening or monitoring.

What screening is recommended for people at increased risk of prostate cancer?
  • Regular PSA blood tests and MRI scans are recommended for men at higher genetic risk.
  • Screening recommendations depend on specific genetic variants and family history.
Can lifestyle changes help lower prostate cancer risk?

Yes, maintaining a healthy lifestyle may help reduce prostate cancer risk. Recommendations include:

  • Eating a balanced diet rich in vegetables and low in processed meats
  • Maintaining a healthy weight
  • Engaging in regular physical activity
  • Avoiding smoking and limiting alcohol intake
Should I consider risk-reducing surgery?

Surgery is rarely recommended for prostate cancer risk reduction, but in certain high-risk cases, doctors may discuss preventive options tailored to your genetic profile.

What are the warning signs of prostate cancer?

It’s important to be aware of symptoms and seek medical advice if you notice:

  • Frequent or difficult urination
  • Blood in the urine or semen
  • Pain in the lower back, pelvis, or hips
  • Erectile dysfunction

Most people with these symptoms do not have cancer, but it's always best to check with a doctor.

Who is at higher risk of prostate cancer?

The risk of prostate cancer increases with age, which is why screening is recommended from age 50. However, additional risk factors include:

  • A family history of prostate, breast, or ovarian cancer
  • African or Caribbean ancestry (higher genetic predisposition)
  • Certain inherited genetic variants

If you have any of these risk factors, talk to your doctor about whether earlier screening is appropriate.

Check4Cancer’s Prostate Screening Test provides screening for men without symptoms aged 40+

Take charge of your prostate health today

Understanding your genetic risk can provide clarity, reassurance, and a proactive path forward. Check4Cancer’s Prostate Cancer Genetic Counselling and Testing service offers expert guidance, personalised insights, and the support you need to make informed decisions about your health.If you are concerned about hereditary risk or would like to explore whether genetic testing is right for you, our specialist team is here to help.

Call us on: 03330 919 650
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"Unbelievably quick and confidential service - made the whole process easy and minimised the anxiety of the results - thank you."
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"Quick, professional and friendly. For what can be a nervous experience, the surroundings and staff helped to ease that."
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Professor Andrew Beggs

Clinical Advisor for Bowel Cancer & Genetics

Professor Andrew Beggs is a Professor of Cancer Genetics & Surgery at the University of Birmingham and University Hospitals Birmingham NHS Foundation Trust. He runs a diverse research group of scientists and clinicians studying the molecular determinants of response to cancer treatments using organoid models and next-generation sequencing models. He is also an active cancer clinician, running a familial cancer clinic for the West Midlands Region and one of the national gastrointestinal polyposis centres. Professor Beggs acts as a scientific adviser to the UK Department of Health and Social Care and Genomics England.

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